"Protein engineering can be defined as the modification of protein structure with recombinant DNA technology or chemical treatment to get a desirable function for better use in medicine, industry and agriculture. It is the process of developing useful or valuable proteins. In this process, a researcher modifies a protein sequence through substitution, insertion, or deletion of nucleotides in the encoding gene, with the goal of obtaining a modified protein that is more suitable for a particular application or purpose than the unmodified protein. There is the conception and production of unnatural polypeptides, often through modification of amino acid sequences that are found in nature. Although protein engineering is often described as being important for future therapeutics, the role of protein engineering is frequently described in a narrow scope: focused primarily on alternative scaffolds which act as antibody substitutes, fusion proteins for increased half-life etc."

Preena N

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