Why is nucleotide metabolism important? Nucleotides have a central role in the physiology of organisms as building blocks of nucleic acids, storage of chemical energy, carriers of activated metabolites for biosynthesis, structural moieties of coenzymes and metabolic regulators. Nucleotide synthesis is important for medical intervention because it can block certain pathways for coming into play. For example it can block the pathway that is responsible for synthesising thymidylate which can help fight against cancer. Cancer is one of the big things that can be fought with this information. Nucleotides are named based on the number of phosphate residues they contain. For example, a nucleotide that has an adenine base and three phosphate residues would be named adenosine triphosphate (ATP). If there is a single phosphate, the nucleotide is adenosine monophosphate (AMP).

Shashank Katariya

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