Alkaloids are a huge group of naturally occurring organic compounds which contain nitrogen atom or atoms (amino or amido in some cases) in their structures. Indole alkaloids are a class of alkaloids containing a structural moiety of indole. Many indole alkaloids also include isoprene groups and are thus called terpene indole or secologanin tryptamine alkaloids. As it contains more than 4100 known different compounds, it is considered as one of the largest classes of alkaloids. Many of them possess significant physiological activity and some of them are used for medicines. Indole alkaloids act on the central and peripheral nervous systems. This is the largest and most interesting alkaloid group derived from tryptophan. Besides, bisindole alkaloids vinblastine and vincristine show antineoplastic effect. Because of structural similarities with serotonin, many tryptamines can interact with serotonin 5-HT receptors. The presentation gives in-depth idea on the topic.

Neethu K Prasanth

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