Any genetic disorders can be determined by checking samples of blood or tissue or even bone marrow and looking for changes in chromosome may be mismatched, rearranged or sometimes extra chromosomes is called cytogenetics. With a combination of molecular biology, identifying chromosomal abnormalities became easier. The basic method used is fluorescence in situ hybridization (FISH). According to this technique, the unique chromosome sequence can be determined. Spectral karyotyping is a technique to recognize all the human chromosomes at one time without a previous knowledge of any disorders. Comparative genomic hybridization is method of estimating the extra number of chromosomes without cell culturing. M-FISH (Multiplex Fluorescence In Situ Hybridization) is a procedure for understanding complex intrachromosomal rearrangements. Detailed information can be obtained out of the PowerPoint presentation.

Janu Padmaprasad

10 resources

0

0

2

Like